Health benefits of pistachios: Improving endothelial function and more

 Nat Prod Res. 2017 Dec 15:1-12. doi: 10.1080/14786419.2017.1408093.

Health benefits of pistachios consumption.

Terzo S1, Baldassano S1, Caldara GF1, Ferrantelli V2, Lo Dico G2, Mulè F1, Amato A1.

Author information

a Department of Biological, Chemical and Pharmaceutical Sciences and Technologies , University of Palermo , Palermo , Italy.
b Istituto Zooprofilattico Sperimentale della Sicilia “A. Mirri” , Palermo , Italy.


The health benefits of nuts, mainly in relation to the improvement of dysmetabolic conditions such as obesity, type 2 diabetes mellitus and the related cardiovascular diseases, have been widely demonstrated. Compared to other nuts, pistachios have a lower fat and caloric content, and contain the highest levels of unsaturated fatty acids, potassium, γ-tocopherol, phytosterols and xanthophyll carotenoids, all substances that are well known for their antioxidant and anti-inflammatory actions. This variety of nutrients contributes to the growing body of evidence that the consumption of pistachios improves health, leading to a greater potential of healthy antioxidant and anti-inflammatory activity, glycemic control, and endothelial function. The present review examines the nutrients and phytochemicals present in pistachios as well as the potential health benefits of including pistachios in a diet.


Pistachio; anti-inflammatory activity; metabolic syndrome; polyphenols; unsaturated fatty acids

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