650-263-7636   contact@endothelix.com             YouTube                                                                       

Guidelines for Endothelial Testing

Archive for the Scientific Updates Category

Microvascular Dysfunction in Peripheral Artery Disease: Is Heat Therapy a Viable Treatment?

Int J Environ Res Public Health 2021 Mar 1;18(5):2384. Microvascular Dysfunction in Peripheral Artery Disease: Is Heat Therapy a Viable Treatment? Cody P Anderson 1 2, Elizabeth J Pekas 1, Song-Young Park 1 Affiliations 1 School of Health and Kinesiology, University of Nebraska at Omaha, Omaha, NE 68182, USA. 2 Department of Biomechanics,

Read more

Will these new iRNA-based LDL and Lp(a) Lowering Rx Make a Significant Impact on US’ Average Cholesterol Level? Probably Not.

J Am Coll Cardiol. 2021 Mar, 77 (12) 1564–1575 New and Emerging Therapies for Reduction of LDL-Cholesterol and Apolipoprotein B: JACC Focus Seminar 1/4 Nick S. Nurmohamed, Ann Marie Navar, and John J.P. Kastelein Abstract Adding to the foundation of statins, ezetimibe and proprotein convertase subtilisin–kexin type 9 inhibitors (PCSK9i), novel, emerging low-density

Read more

Diastolic Dysfunction vs. Endothelial Dysfunction

Eur J Clin Invest 2021 Mar 22 Clinical assessment of endothelial function in heart failure with preserved ejection fraction: A meta-analysis with meta-regressions Pasquale Ambrosino 1, Antimo Papa 1, Agostino Buonauro 2, Marco Mosella 1, Ilenia Calcaterra 3, Giorgio Alfredo Spedicato 4, Mauro Maniscalco 1, Matteo Nicola Dario Di Minno 5 Affiliations collapse Affiliations 1 Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy. 2

Read more

Brain Endothelium in Health and Disease

Am J Pathol 2021 Mar 10 ENDOTHELIAL CONTROL OF CEREBRAL BLOOD FLOW Julianne W Ashby 1, Julia J Mack 2 Affiliations 1 Department of Medicine, Division of Cardiology, University of California, Los Angeles. 2 Department of Medicine, Division of Cardiology, University of California, Los Angeles. Electronic address: JMack@mednet.ucla.edu. Abstract Since constant perfusion

Read more

New noninvasive approaches to the endothelium as a therapeutic target

Front Physiol 2021 . The Endothelium as a Therapeutic Target in Diabetes: A Narrative Review and Perspective Jose A Adams, Arkady Uryash, Jose R Lopez, Marvin A Sackner Affiliations collapse Affiliations Mount Sinai Medical Center, Miami Beach, FL, United States. Abstract Diabetes has reached worldwide epidemic proportions, and threatens to be

Read more

New insights into the role of INF in “hyperinflammation”, endothelial injury, and two different COVID outcomes

Transl Res 2021 Mar 5;S1931-5244(21)00052-9. COVID-19 and Cytokine Storm Syndrome: Are there lessons from Macrophage Activation Syndrome? Michael J Ombrello 1, Grant S Schulert 2 Affiliations 1 Translational Genetics and Genomics Unit, Pediatric Translational Research Branch, Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, 10 Center

Read more

Why Is COVID-19 More Severe in Patients With Diabetes?

Why Is COVID-19 More Severe in Patients With Diabetes? The Role of Angiotensin-Converting Enzyme 2, Endothelial Dysfunction and the Immunoinflammatory System Jacob Roberts 1, Antonia L Pritchard 1, Andrew T Treweeke 1, Adriano G Rossi 2, Nicole Brace 1, Paul Cahill 3, Sandra M MacRury 1, Jun Wei 1, Ian L Megson 1 Affiliations 1 Institute for Health Research and Innovation, University of the

Read more

How to use endothelial function testing to detect “Residual Risk”

Practical Guidelines for Endothelial Function Testing in Primary Prevention and Detecting “Residual Risk” in Secondary Prevention Download Slides Download Papers Scientific Updates Sponsored by Endothelix Inc. View Archive

Read more

Keto diet improves endothelial function with “pleotropic” role of βOHB –Published in JACC Focus Seminar

Therapeutic Potential of Ketone Bodies for Patients With Cardiovascular Disease: JACC Focus Seminar Salva R Yurista 1, Cher-Rin Chong 2, Juan J Badimon 3, Daniel P Kelly 4, Rudolf A de Boer 5, B Daan Westenbrink 6 Affiliations 1 University Medical Center Groningen, University of Groningen, Department of Cardiology, Groningen, the Netherlands. Electronic address: https://twitter.com/salvareverentia. 2 Basil Hetzel

Read more

Dr. Fuster’s top 100 picks from JACC 2020 and Dr. Naghavi’s top 5

JACC Editor-in-Chief’s Top 100 Picks Valentin Fuster, MD, PhD Each week, I record audio summaries for every paper in JACC, as well as an issue summary. Although this process is quite time-consuming, I have become familiar with every paper that we publish. Thus, I have personally selected the

Read more