Clinical Studies:

• Predictive value of reactive hyperemia for cardiovascular events in patients with peripheral arterial disease undergoing vascular surgery. Huang AL et al Arterioscler Thromb Vasc Biol. 2007 Oct;27(10):2113-9.

• Statins enhance postischemic hyperemia in the skin circulation of hypercholesterolemic patients: a monitoring test of endothelial dysfunction for clinical practice? Binggeli C et al J Am Coll Cardiol. 2003 Jul 2; 42(1):71-7.

• Statins, skin, and the search for a test of endothelial function. Celermajer DS JACC Vol. 42, No. 1, 2003 Celermajer 79 July 2, 2003:78–80

• Postischemic forearm skin reactive hyperemia is related to cardiovascular risk factors in a healthy female population. Vuilleumier P et al J Hypertens. 2002 Sep; 20(9):1753-7.

• Postischemic blood flow response in hypercholesterolemic patients. Hayoz D et al Hypertension. 1995; 26:497-502

• Individuals at increased coronary heart disease risk are characterized by an impaired microvascular function in skin. IJzerman RG et al Eur J Clin Invest. 2003 Jul; 33(7):536-42.

• Skin blood flowmotion and microvascular reactivity investigation in hypercholesterolemic patients without clinically manifest arterial diseases. Rossi M et al Physiol Res. 2008 Jan 17

• Microvascular and macrovascular reactivity is reduced in subjects at risk for type 2 diabetes. Caballero AE et al Diabetes, Vol 48, September 1999

• How microcirculation data have changed my clinical practice. Bu¨chele GL et al Current Opinion in Critical Care 2007, 13:324–331

• Reactive hyperemia and cardiovascular risk. Philpott A, Anderson TJ.Arterioscler Thromb Vasc Biol. 2007 Oct; 27(10):2065-7.

• Reactive hyperemia revisited. Calderaro D et al Arterioscler Thromb Vasc Biol. 2008 Apr; 28(4):e23-4; author reply e25.

• Are vascular function measurements ready for the clinic? Wilson AM et al European Heart Journal (2006) 27, 255–257

• Cross-sectional relations of digital vascular function to cardiovascular risk factors in the framingham heart study. Hamburg N Circulation 2008; 117;2467-2474

• Reliable endothelial function testing: at our fingertips? Celermajer DS Circulation 2008; 117;2428-2430

• Wearing your heart in your sleeve? Hughes AD and Thom S European Heart Journal (2001) 22, 1071–1073

• Peripheral arterial responses to treadmill exercise among healthy subjects and atherosclerotic patients. Rozanski A Circulation, Apr 2001; 103: 2084 - 2089

• The post-occlusive hyperemic response in patients with systemic sclerosis. Wigley FM et al Arthritis and Rheumatism Vol.33, No. 11, November 1990

• Endothelial function predicts future development of coronary artery disease. Bugiardini R et al Circulation. 2004; 109:2518-2523

• Prognostic value of systemic endothelial dysfunction in patients with acute coronary syndromes further evidence for the existence of the “vulnerable” patient. Fichtlscherer S et al Circulation. 2004; 110:1926-1932

• Assessment of peripheral vascular endothelial function with finger arterial pulse wave amplitude. Kuvin J et al American Heart Journal Volume 146, Number 1

• Brachial artery vasodilator function and systemic inflammation in the Framingham offspring study. Vita JA et al Circulation. 2 2004;110:3604-3609.

• Close relationship between the vasodilator response to acetylcholine in the brachial and coronary artery in suspected coronary artery disease. Takase B et al International Journal of Cardiology 105 (2005) 58– 66

• Cutaneous vascular reactivity is reduced in aging and in heart failure: association with inflammation. Andersson SE et al Clinical Science (2003) 105, 699–707

• Tissue doppler imaging a new prognosticator for cardiovascular diseases. CM Yu et al JACC Vol. 49, No. 19, 2007

Basic Physiology Studies:

• Skin temperature changes and changes in skin blood flow monitored with laser doppler flowmetry and imaging: a methodological study in normal humans. Bornmyr S et al Clinical Physiology (1997) 17, 71–81

• The human cutaneous circulation as a model of generalized microvascular function. Holowatz LA et al J Appl Physiol 105: 370–372, 2008

• The investigation of skin blood flowmotion: a new approach to study the microcirculatory impairment in vascular diseases? Rossi M et al Biomedicine & Pharmacotherapy 60 (2006) 437–442

• Microvascular blood flow and skin temperature changes in the fingers following a deep inspiratory gasp. Allen J et al Physiol. Meas. 23 (2002) 365–373

• Technical aspects of evaluating brachial artery vasodilatation using high frequency ultrasound. Corretti MC et al American Journal of Physiology - Heart and Circulatory Physiology Volume 268, Issue 4 37-4, 1995

• Evaluation of the microcirculation in hypertension and cardiovascular disease. Struijker-Boudier HAJ et al European Heart Journal (2007) 28, 2834–2840

• Role of nitric oxide in the regulation of digital pulse volume amplitude in humans. Anju Nohria A et al J Appl Physiol 101: 545–548, 2006

• In FMD, NO is actually "the middle man." Wray DW and Richardson RS J Appl Physiol 99:1624-, 2005.

• Flow-mediated dilation and biological variability. Thomas G J Appl Physiol 99:1626-, 2005.

• Flow-mediated vasodilation partially reflects nitric oxide-mediated endothelial function. Linke A et al J Appl Physiol 99:1622-, 2005.

• The relationship between shear stress and flow-mediated dilatation: implications for the assessment of endothelial function. Kyra E Pyke and Michael E Tschakovsky J. Physiol. 2005; 568; 357-369

• Why is flow-mediated dilation dependent on arterial size? Assessment of the shear stimulus using phase-contrast magnetic resonance imaging. Silber H et al Am J Physiol Heart Circ Physiol 288: H822–H828, 2005